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Intranasal Tapentadol vs Intravenous Paracetamol for pain in Lower Limb Orthopaedic Surgeries
November 2024
Intranasal Tapentadol vs Intravenous Paracetamol for pain in Lower Limb Orthopaedic Surgeries
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Intranasal Tapentadol Versus Intravenous Paracetamol for Postoperative Analgesia in Lower Limb Orthopaedic Surgeries Under Spinal Anaesthesia: A Single Blind RCT.
Clin J Pain . 2024 Aug 1;40(8):463-468.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Seventy-four patients undergoing lower limb orthopedic surgeries under spinal anesthesia were randomized to receive either intranasal tapentadol (44.5 mg, n=37) or intravenous paracetamol (1 g, n=37) every 6 hours for 72 hours, starting 3 hours after surgery. The primary outcome was pain intensity measured by the Visual Analog Scale (VAS). Secondary outcomes included systolic blood pressure (SBP),...
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