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Intravenous Tranexamic Acid on Perioperative Blood Loss in Total Knee Arthoplasty
February 2025
Intravenous Tranexamic Acid on Perioperative Blood Loss in Total Knee Arthoplasty
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
The Effect of Intravenous Tranexamic Acid on Perioperative Blood Loss, Transfusion Requirements, Verticalization, and Ambulation in Total Knee Arthroplasty: A Randomized Double-Blind Study.
Medicina (Kaunas) . 2024 Jul 21;60(7):1183.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Ninety-six patients undergoing primary total knee arthroplasty (TKA) were randomized to receive intravenous tranexamic acid (TXA) at two time points (n=48) or a placebo of 0.9% saline solution (n=48). The primary outcome was perioperative blood loss. Secondary outcomes included transfusion requirements, time to verticalization, and time to ambulation. Outcomes were assessed up to postoperative day...
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