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Gabapentinoids on Pain-Related Outcomes after Knee and Hip Surgery
November 2024
Gabapentinoids on Pain-Related Outcomes after Knee and Hip Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
The Impact of Gabapentinoids on Pain-Related Outcomes after Knee and Hip Surgery: A Systematic Review with Meta-Analysis of Randomized Controlled Trials.
J Clin Med . 2024 Jul 18;13(14):4205. doi: 10.3390/jcm13144205.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Fifteen studies including 1,320 patients undergoing knee or hip surgery were included in this systematic review and meta-analysis, comparing gabapentinoid use (gabapentin or pregabalin) with a placebo. Pooled outcomes of interest included pain intensity at rest and on movement, opioid consumption, postoperative nausea, and postoperative vomiting. Gabapentinoid use was associated with a modest redu...
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