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Efficacy of Diosmin In Reducing Lower-Extremity Swelling & Pain After Total Knee Arthroplasty

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Ace Report Cover
August 2024

Efficacy of Diosmin In Reducing Lower-Extremity Swelling & Pain After Total Knee Arthroplasty

Vol: 306| Issue: 8| Number:49| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Efficacy of Diosmin in Reducing Lower-Extremity Swelling and Pain After Total Knee Arthroplasty: A Randomized, Controlled Multicenter Trial.

J Bone Joint Surg Am . 2024 Mar 20;106(6):492-500.

Contributing Authors:
Q Wang Q Jin L Cai C Zhao P Feng J Jia W Xu Q Qian Z Ding J Xu C Gu S Zhang H Shi H Ma Y Deng T Zhang Y Song Y Zhang X Zhou L Pei Y Yang J Liang T Jiang H Li H Liu L Wu P Kang

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Synopsis

Three hundred thirty patients undergoing primary unilateral total knee arthroplasty for osteoarthritis were randomized to receive diosmin (n=167) or no diosmin (n=163). The diosmin group received 0.9 g twice daily for 14 days postoperatively, while the control group received no treatment or placebo. The primary outcome of interest was lower-extremity swelling measured at 24, 48, and 72 hours, and ...

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