AAOS 2024: High Molecular Weight Hyaluronic Acid Injection for Knee Osteoarthritis
AAOS 2024: High Molecular Weight Hyaluronic Acid Injection for Knee Osteoarthritis
High molecular weight hyaluronic acid injection had similar outcome to saline in knee osteoarthritis: a randomized double-blind, placebo-controlled trial
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Synopsis
276 patients with primary knee osteoarthritis were randomized to receive either a single-shot intraarticular cross-linked hyaluronic acid (HA) injection (hyruan-one), high molecular weight HA (hylan G-F 20), or saline control. The primary outcome of interest was pain at rest and with movement on a Visual Analog Scale (VAS) after 24 weeks and a change from baseline scores. Secondary outcomes includ...
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