One hundred twenty-eight patients with knee osteoarthritis were randomized to receive prolotherapy with 5% dextrose (n=30), 10% dextrose (n=30), 20% dextrose (n=30), or exercise plus hotpack only (n=30). All prolotherapy groups received three injection sessions at weeks 0, 3, and 6, combined with a home exercise program and hotpack therapy. The primary outcome was pain assessed by VAS. Secondary o...