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Preoperative Tranexamic Acid Reduces Transfusion in DHS Surgery for Hip Fractures
August 2025
Preoperative Tranexamic Acid Reduces Transfusion in DHS Surgery for Hip Fractures
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Efficacy of preoperative Tranexamic Acid in patients undergoing intertrochanteric hip fracture surgery: A randomized placebo controlled trial.
Pak J Med Sci . 2023 Nov-Dec;39(6):1601-1605.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Two hundred patients with intertrochanteric hip fractures were randomized to receive either a single preoperative dose of IV tranexamic acid (15 mg/kg in 100 ml saline, n=100) or placebo (100 ml saline, n=100). The primary outcome was frequency of perioperative allogenic blood transfusion. Secondary outcomes included perioperative hemoglobin changes, number of transfusion packs required, and post-...
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