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Spinal vs General Anesthesia for Muscle Weakness in Bilateral Hip Arthroplasty
September 2025
Spinal vs General Anesthesia for Muscle Weakness in Bilateral Hip Arthroplasty
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
The effect of spinal versus general anaesthesia on perioperative muscle weakness in patients having bilateral total hip arthroplasty: a single center randomized clinical trial.
Eur J Med Res . 2023 Oct 20;28(1):450.Synopsis
Forty-six patients undergoing bilateral THA were randomized to receive spinal anesthesia (SA) with monitored anesthesia care (n=23) or general anesthesia (GA) (n=23). The primary outcome was change in handgrip strength on postoperative day 1 relative to baseline. Secondary outcomes included maximal inspiratory pressure (MIP), EQ-5D-5L health status, and biomarkers of the stress response (ACTH, cor...
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