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Thrombin-Based Hemostatic Agent in Total Knee Arthroplasty: A Meta-Analysis

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May 2024

Thrombin-Based Hemostatic Agent in Total Knee Arthroplasty: A Meta-Analysis

Vol: 306| Issue: 5| Number:10| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Effects of Thrombin-Based Hemostatic Agent in Total Knee Arthroplasty: Meta-Analysis.

J Orthop Surg Res . 2014 Oct 15:9:90.

Contributing Authors:
JW Park TW Kim CB Chang M Han JJ Go BK Park WL Jo YK Lee

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Synopsis

Eight randomized controlled trials (904 patients) comparing a thrombin-based hemostatic agent, Floseal, against control for total knee arthroplasty (TKA) were included in this systematic review and meta-analysis. Outcomes of interest included a decrease in hemoglobin, drainage volume, total blood loss, and the incidence of allogeneic blood transfusion. The decrease in hemoglobin and the incidence ...

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