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Epidural Morphine and Bupivacaine For Post-Op Analgesia After Transforaminal Lumbar Interbody Fusion

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Ace Report Cover
June 2025

Epidural Morphine and Bupivacaine For Post-Op Analgesia After Transforaminal Lumbar Interbody Fusion

Vol: 307| Issue: 6| Number:122| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

A Randomised Controlled Study on Epidural Morphine and Bupivacaine for Post-Operative Analgesia After Transforaminal Lumbar Interbody Fusion.

Global Spine J . 2023 Sep;13(7):1926-1931.

Contributing Authors:
DR Kanna DS Jakkepally DAP Shetty DS Rajasekaran

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Synopsis

One hundred patients undergoing transforaminal lumbar interbody fusion (TLIF) for various lumbar pathologies were randomized to receive either an intraoperative epidural instillation of morphine 5 mg with 2 mL of 0.25% bupivacaine and additional 6 mL bupivacaine infiltration into deep fascia (n=50), or no such instillation (n=50). The primary outcome was post-operative pain, assessed using VAS and...

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