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Efficacy of Tumor Necrosis Factor Inhibitors in Hand Osteoarthritis: a Meta-Analysis
March 2024
Efficacy of Tumor Necrosis Factor Inhibitors in Hand Osteoarthritis: a Meta-Analysis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Efficacy of tumor necrosis factor inhibitors in hand osteoarthritis: A systematic review and meta-analysis of randomized controlled trials.
Osteoarthr Cartil Open . 2023 Aug 12;5(4):100404.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
In this overview of four randomized controlled trials with parallel group and cross-over design, a total of 276 patients with hand osteoarthritis (OA) were randomized to receive tumor necrosis factor inhibitors (TNF inhibitors), such as adalimumab or etanercept, versus a placebo treatment. The primary outcome of interest was pain reduction measured by visual analog scale (VAS) and the Australian/C...
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