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Vancomycin Versus Cefazolin in the Prevention of Surgical Site Infections Following TKA
December 2023
Vancomycin Versus Cefazolin in the Prevention of Surgical Site Infections Following TKA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Is Topical Vancomycin an Option? A Randomized Controlled Trial to Determine the Safety of the Topical Use of Vancomycin Powder in Preventing Postoperative Infections in Total Knee Arthroplasty, as Compared With Standard Postoperative Antibiotics.
J Arthroplasty . 2023 Aug;38(8):1597-1601.e1.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
165 patients undergoing total knee arthroplasty were randomized to receive either vancomycin (n=80) or cefazolin (n=85). The primary outcome of this trial was the incidence of surgical site infections (SSI) after 42 postoperative days. Secondary outcomes of interest include length of stay, the incidence of postoperative myocardial infarction (MI), pulmonary embolism (PE), urinary tract infection, ...
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