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Topical Versus Intravenous Tranexamic Acid On Opioid Consumption & Pain for Total Hip Arthroplasty
August 2023
Topical Versus Intravenous Tranexamic Acid On Opioid Consumption & Pain for Total Hip Arthroplasty
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Topical use of tranexamic acid can reduce opioid consumption compared with intravenous use for patients undergoing primary total hip arthroplasty: a prospective randomized controlled trial.
BMC Musculoskelet Disord . 2023 Jun 3;24(1):455.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
161 patients undergoing total hip arthroplasty for end-stage hip osteoarthritis were randomized to receive either topical tranexamic acid (TXA; n=82) or intravenous TXA (n=79). The primary outcomes of interest included postoperative pain on a Visual Analog Scale (VAS) and tramadol consumption for the first three postoperative days. Secondary outcomes included C-reactive protein (CRP) levels, eryth...
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