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AAOS 2023: Oral Versus Intravenous Tranexamic Acid for Primary Total Hip or Knee Arthroplasty

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Ace Report Cover
March 2023

AAOS 2023: Oral Versus Intravenous Tranexamic Acid for Primary Total Hip or Knee Arthroplasty

Vol: 303| Issue: 3| Number:20| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Comparing the Effectiveness of Oral versus Intravenous Tranexamic Acid in Primary Total Hip and Knee Arthroplasty: A Randomized Trial

Contributing Authors:
PK Sculco C Defrancesco J Reichel EC Gbaje M Popovic A Gonzalez Della Valle MB Cross AS Ranawat SG Memtsoudis

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CONFERENCE ACE REPORTS

This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.

Synopsis

Four hundred patients undergoing total knee arthroplasty (TKA; n=200) or total hip arthroplasty (THA; n=200) were randomized to receive either oral (n=200) versus intravenous (IV) tranexamic acid (TXA) (n=200) preoperatively. Patients were randomized using a 1:1 block size within each surgery group. The primary outcome of this trial was calculated blood loss (CBL) based on the hematocrit levels on...

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