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Subcutaneous Abaloparatide in Men with Osteoporosis

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Ace Report Cover
February 2023

Subcutaneous Abaloparatide in Men with Osteoporosis

Vol: 303| Issue: 2| Number:5| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

The Efficacy and Safety of Abaloparatide-SC in Men With Osteoporosis: A Randomized Clinical Trial

J Bone Miner Res. 2022 Dec;37(12): 2435-2442.

Contributing Authors:
E Czerwinski J Cardona R Plebanski C Recknor T Vokes KG Saag N Binkley EM Lewiecki J Adachi D Knychas D Kendler E Orwoll Y Chen L Pearman YH Li B Mitlak

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Synopsis

Two hundred and twenty-eight men with osteoporosis were randomized to receive 12 months of daily subcutaneous abaloparatide (n=149) or placebo (n=79). The primary outcome of interest was the change from baseline in lumbar spine bone mineral density (BMD). Secondary outcomes of interest include BMD of the femoral neck and hip and the incidence of new clinical fractures; safety outcomes were also as...

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