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Topical vs. Oral NSAIDs for Treatment of Osteoarthritis
November 2022
Topical vs. Oral NSAIDs for Treatment of Osteoarthritis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Relative safety and efficacy of topical and oral NSAIDs in the treatment of osteoarthritis: A systematic review and meta-analysis
Medicine (Baltimore) . 2022 Sep 9;101(36):e30354.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Eight randomized trials containing a total of 2096 patients with osteoarthritis were included in this systematic review and meta-analysis comparing topical and oral non-steroidal anti-inflammatory drugs (NSAIDs). Pooled outcomes of interest included the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain and stiffness sub-scores, pain on a Visual Analog Scale (VAS), and the...
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