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Early Bisphosphonate Therapy on Time to Fracture Healing in Proximal Femur Fixation

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Ace Report Cover
August 2022

Early Bisphosphonate Therapy on Time to Fracture Healing in Proximal Femur Fixation

Vol: 282| Issue: 1| Number:3| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Early bisphosphonate therapy post proximal femoral fracture fixation does not impact fracture healing: a systematic review and meta-analysis

ANZ J Surg . 2022 Jun 2. doi: 10.1111/ans.17792

Contributing Authors:
YYF Tong S Holmes A Sefton

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Synopsis

A meta-analysis of six randomized controlled trials comparing the effect of early administration of bisphosphonate therapy or control (delayed) administration of bisphosphonates on time to fracture healing was conducted. Outcomes of interest were time to fracture healing, rates of delayed union, non-union, and revision surgery. The mean time to fracture healing was shorter in patients who received...

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