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Leukocyte-Rich vs. Leukocyte-Poor Platelet-Rich Plasma for Knee Osteoarthritis

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Ace Report Cover
July 2021

Leukocyte-Rich vs. Leukocyte-Poor Platelet-Rich Plasma for Knee Osteoarthritis

Vol: 254| Issue: 1| Number:1| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Leukocyte-Rich versus Leukocyte-Poor Platelet-Rich Plasma for the Treatment of Knee Osteoarthritis: A Double-Blind Randomized Trial

Am J Sports Med. 2022 Mar;50(3): 609-617.

Contributing Authors:
A Di Martino A Boffa L Andriolo I Romandini SA Altamura A Cenacchi V Roverini S Zaffagnini G Filardo

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Synopsis

192 patients with unilateral, symptomatic knee osteoarthritis were randomized to receive 3 weekly intra-articular injections of leukocyte-rich platelet-rich plasma (n=96) or leukocyte-poor platelet-rich plasma (n=96). The primary outcome of interest was the International Knee Documentation Committee (IKDC) score at 12 months. Secondary outcomes of interest included the Knee Injury and Osteoarthrit...

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