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Effect of Carbazochrome Sodium Sulfonate plus Tranexamic Acid for Hemostasis and Inflammation in TKA

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Ace Report Cover
March 2022

Effect of Carbazochrome Sodium Sulfonate plus Tranexamic Acid for Hemostasis and Inflammation in TKA

Vol: 212| Issue: 1| Number:1| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Effects of carbazochrome sodium sulfonate combined with tranexamic acid on hemostasis and inflammation during perioperative period of total hip arthroplasty: A randomized controlled trial

Orthop Traumatol Surg Res. 2022 Feb;108(1): 103092.

Contributing Authors:
Y Luo Y Releken D Yang Y Yue Z Liu P Kang

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Synopsis

One hundred and fifty patients undergoing a total hip arthroplasty were randomized to receive carbazochrome sodium sulfate plus tranexamic acid (n=50), tranexamic acid only (n=50) or placebo (n=50). The primary outcome of interest was total blood loss. Secondary outcomes of interest included hemoglobin levels, coagulation and inflammatory markers, pain on a Visual Analog Scale (VAS), length of sta...

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