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Topical Tranexamic Acid After Wound Incision in Acute Thoracolumbar Burst Fracture Surgery
November 2021
Topical Tranexamic Acid After Wound Incision in Acute Thoracolumbar Burst Fracture Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
The influence of topical use of tranexamic acid in reducing blood loss on early operation for thoracolumbar burst fracture: a randomized double-blinded controlled study
Eur Spine J. 2021 Oct;30(10): 3074-3080.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Ninety-three patients with acute thoracolumbar burst fractures scheduled for an open decompression, fracture reduction and internal fixation procedure were randomized to receive topical tranexamic acid (n=46) or normal saline (n=47) after wound incision for the reduction of blood loss. Outcomes of interest included blood loss (intra-operative, post-operative, total, hidden), operative time, hemogl...
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