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PRP Combined with Hyaluronic Acid vs. Autologous Microfragmented Adipose Tissue for Early Knee OA

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Ace Report Cover
September 2021

PRP Combined with Hyaluronic Acid vs. Autologous Microfragmented Adipose Tissue for Early Knee OA

Vol: 93| Issue: 1| Number:1| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

A Prospective Study Comparing Leukocyte-Poor Platelet-Rich Plasma Combined with Hyaluronic Acid and Autologous Microfragmented Adipose Tissue in Patients with Early Knee Osteoarthritis.

Stem Cells Dev. 2021 Jul 1;30(13): 651-659.

Contributing Authors:
I Dallo D Szwedowski A Mobasheri E Irlandini A Gobbi

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Synopsis

Fifty patients (80 knees) were randomized to receive a single injection of autologous microfragmented adipose tissue (AMAT; n=25, 40 knees) or 3 monthly injections of leukocyte-poor platelet-rich plasma (PRP) plus hyaluronic acid (HA) (n=25, 40 knees). The primary outcomes of interest were pain, symptoms and activity level. Outcomes were assessed at 6 and 12 months follow up. Results revealed no s...

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