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Zoledronic Acid After Percutaneous Kyphoplasty for Osteoporotic Fx Improves Pain, Disability & BMD
May 2021
Zoledronic Acid After Percutaneous Kyphoplasty for Osteoporotic Fx Improves Pain, Disability & BMD
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Clinical efficacy of zoledronic acid combined with percutaneous kyphoplasty in the prevention and treatment of osteoporotic vertebral compression fracture: A systematic review and meta-analysis
Medicine (Baltimore). 2021 Apr 2;100(13): e25215.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Eight randomized controlled trials including 578 patients with osteoporotic vertebral compression fracture who underwent percutaneous kyphoplasty were randomized to undergo zoledronic acid injections (n=285) or no treatment (n=293). Primary outcomes included bone mineral density (BMD), pain on the visual analogue scale (VAS), disability using the Oswestry Disability Index (ODI), incidence of recom...
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