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Rosuvastatin to Decrease Risk of Fracture - JUPITER RCT trial
March 2025
Rosuvastatin to Decrease Risk of Fracture - JUPITER RCT trial
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Statin therapy and risk of fracture: results from the JUPITER randomized clinical trial
JAMA Intern Med. 2015 Feb;175(2):171-7.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Seventeen thousand eight hundred two patients with no history of cardiovascular disease or diabetes but with elevated hs-CRP were randomized to receive rosuvastatin 20 mg daily (n=8,901) or placebo (n=8,901). The primary outcome of interest was incident fracture. Secondary outcomes included subgroup effects by sex and hs-CRP tertiles, as well as site-specific fracture rates. Outcomes were assessed...
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