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Perioperative Ketamine Effectively Reduces Post-Operative Pain and Opioid Consumption in THA and TKA

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Ace Report Cover
December 2020

Perioperative Ketamine Effectively Reduces Post-Operative Pain and Opioid Consumption in THA and TKA

Vol: 9| Issue: 12| Number:9| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Analgesic effect of perioperative ketamine for total hip arthroplasties and total knee arthroplasties: A PRISMA-compliant meta-analysis.

Medicine (Baltimore). 2020 Oct 16; 99(42): e22809.

Contributing Authors:
P Wang Z Yang S Shan Z Cao Z Wang

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Synopsis

Twenty-one studies including 1145 patients undergoing total hip or knee arthroplasty were included in this meta-analysis comparing peri-operative ketamine and control for the management of post-operative pain and reduction of opioid consumption. Pooled outcomes of interest included pain on a Visual Analog Scale (VAS), opioid consumption in morphine equivalents, and the incidence of side effects (i...

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