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IV and topical tranexamic acid protocols reduce blood loss and transfusion needs in THA
November 2018
IV and topical tranexamic acid protocols reduce blood loss and transfusion needs in THA
Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A
The Efficacy of Tranexamic Acid in Total Hip Arthroplasty: A Network Meta-analysis
J Arthroplasty. 2018 Oct;33(10):3083-3089.e4. doi: 10.1016/j.arth.2018.06.023Synopsis
Data from 31 randomized controlled trials on blood loss, and from 16 randomized controlled trials on transfusion rate, were included in this network metaanalysis comparing outcome between various tranexamic acid (TXA) administration strategies, including intravenous (IV), intraarticular/topical (IA), and oral TXA, and placebo in patients who underwent total hip arthroplasty. When assessing blood l...
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