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Parecoxib use reduces pain and opioid consumption post-total knee arthroplasty compared to placebo
November 2018
Parecoxib use reduces pain and opioid consumption post-total knee arthroplasty compared to placebo
Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A
The efficacy and safety of parecoxib for reducing pain and opioid consumption following total knee arthroplasty: A meta-analysis of randomized controlled trials
Int J Surg. 2018 Nov;59:67-74Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
4 randomized controlled trials were included in this meta-analysis, investigating the safety and effectiveness of parecoxib use compared to placebo in postoperative analgesia following total knee arthroplasty (TKA). Outcomes of interest included knee pain and morphine consumption, measured at 6, 12 and 24 hours. Results from the meta-analysis found that postoperative parecoxib use resulted in bett...
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