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Synovial biomarkers and clincial scores of Orthovisc versus Hylan G-F20 in knee OA treatment
April 2019
Synovial biomarkers and clincial scores of Orthovisc versus Hylan G-F20 in knee OA treatment
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Effects of different hyaluronic acid products on synovial fluid levels of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in knee osteoarthritis.
Ann Clin Lab Sci. 2004 Summer;34(3):330-5Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
40 patients with knee osteoarthritis were randomized to three weekly injections of either Orthovisc (Anika Therapeutics) or Hylan G-F20 (Synvisc; Genzyme). Primary outcomes were synovial fluid concentrations of intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1). Clinical outcome on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) was...
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