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IA ketorolac has no significant analgesic effect relative to placebo for post-knee arthroscopy pain

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Ace Report Cover
February 2019

IA ketorolac has no significant analgesic effect relative to placebo for post-knee arthroscopy pain

Vol: 8| Issue: 2| Number:108| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:1
Journal Level of Evidence:N/A

Randomized controlled trial of intra-articular ketorolac on pain and inflammation after minor arthroscopic knee surgery

Acta Anaesthesiol Scand. 2018 Jul;62(6):829-838

Contributing Authors:
N Solheim I Gregersen B Halvorsen V Bjerkeli A Stubhaug T Gordh LA Rosseland

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Synopsis

44 patients with moderate to severe pain following minor knee arthroscopy were randomized to an intraarticular injection of ketorolac or placebo. Patients were assessed for pain scores over the first 120 minutes after administration, intravenous rescue analgesia consumption, and synovial concentrations of CXCL1, IL-8, and MCP-1 from microdialysis. Results demonstrated no significant differences be...

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