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Nabilone improves sleep compared to amitriptyline in fibromyalgia patients over 2 weeks

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Ace Report Cover
September 2018

Nabilone improves sleep compared to amitriptyline in fibromyalgia patients over 2 weeks

Vol: 7| Issue: 9| Number:2| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

The effects of nabilone on sleep in fibromyalgia: results of a randomized controlled trial

Anesth Analg. 2010 Feb 1;110(2):604-10. doi: 10.1213/ANE.0b013e3181c76f70

Contributing Authors:
MA Ware M Fitzcharles L Joseph Y Shir

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Synopsis

32 patients with fibromyalgia were randomized to receive either 0.5 mg nabilone or 10 mg amitriptyline over 2 weeks, with a possibility of doubling the dose after 1 week. Patients then underwent a 2-week washout period, and then received the opposite treatment to the first phase. The purpose of this study was to compare whether nabilone improved sleep compared to amitriptyline, and whether the two...

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