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Floseal hemostatic agent reduces blood loss but not transfusion needs in TKA patients
J Arthroplasty. 2014 Oct;29(10):1950-5.
Thrombin-based hemostatic agent associated with reduced drain output & transfusion in TKA
Knee Surg Relat Res. 2014 Dec;26(4):236-40
Collagen/thrombin and autologous platelet hemostatic agent reduces transfusion during TKA
J Arthroplasty. 2012 May;27(5):695-702. Epub 2011 Oct 27
Efficacy of Floseal vs. tranexamic acid vs. control for bleeding control in patients undergoing TKA
Clinics (Sao Paulo). 2019 Nov 25;74:e1186.
Decreased impairment of blood coagulation through the use of low molecular-weight colloid
Korean J Anesthesiol. 2015 Aug;68(4):364-72.
Low tourniquet pressure provides similar efficacy and safety to standard tourniquet pressure in TKA
BMC Musculoskelet Disord. 2019 Jun 4;20(1):275. doi: 10.1186/s12891-019-2636-7
Local TXA Reduces Blood Loss vs Intravenous TXA in Patients Undergoing Total Hip Replacement
Adv Ther. 2020 01-Oct;():. 10.1007/s12325-020-01454-3
IV & topical TXA similarly safe & effective for reducing blood loss and transfusion in TKA
J Orthop. 2016 Mar 26;13(3):127-31
TKA: Drain-clamping with tranexamic acid decreased drained blood volume/ transfusions
BMC Musculoskelet Disord. 2012 Jul 20;13:124. doi: 10.1186/1471-2474-13-124
TKA: No effect of fibrin sealant on reducing blood loss and functional recovery
Acta Orthop. 2013 Apr;84(2):153-8. doi: 10.3109/17453674.2013.769082. Epub 2013 Jan 25
Similar Clinical Outcomes in Oral TXA vs Epsilon-Aminocaproic Acid Up to 30 Days After THA Surgery
Blood Coagul Fibrinolysis. 2021 01-Mar;():. 10.1097/MBC.0000000000001005
Combined IV and topical tranexamic acid reduces blood loss, not transfusion rate, in TKA
J Arthroplasty. 2016 Feb;31(2):542-7
Topical tranexamic acid in TKA effectively reduces blood loss in patients
J Arthroplasty. 2013 Sep;28(8 Suppl):78-82
Preop oral TXA demonstrates noninferiority to IV TXA in TKA for hemostasis
J Arthroplasty. 2016 Sep;31(9 Suppl):26-30
Thrombin-JMI in TKA minimizes hemoglobin reduction but may not be cost effective
J Arthroplasty. 2013 Sep;28(8):1278-81
No effect of topical fibrinogen spray on blood loss and transfusion in TKA
Clin Orthop Relat Res. 2014 Jan;472(1):272-6. doi: 10.1007/s11999-013-3036-1
Three doses of 15mg/kg IV TXA reduces blood loss vs. placebo in trochanteric fracture surgery
Hong Kong Med J. 2019 Apr;25(2):120-126.