
Efficacy of topical diclofenac preparation in managing symptomatic knee osteoarthritis

Efficacy of topical diclofenac preparation in managing symptomatic knee osteoarthritis
Effect of a topical diclofenac solution for relieving symptoms of primary osteoarthritis of the knee: a randomized controlled trial
CMAJ. 2004 Aug 17;171(4):333-8Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
248 patients with symptomatic knee osteoarthritis were randomized to one of three treatment groups: topical diclofenac sodium gel, a vehicle-control group that administered only the carrier solution, and a placebo group. Patients were to apply the allocated interventions for 4 weeks. Patients were assessed for outcome on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), a...
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