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Efficacy of various celecoxib doses versus naproxen and placebo in knee osteoarthritis treatment
September 2017
Efficacy of various celecoxib doses versus naproxen and placebo in knee osteoarthritis treatment
Study Type:Therapy
OE Level Evidence:N/A
Journal Level of Evidence:N/A
Treatment of osteoarthritis with celecoxib, a cyclooxygenase-2 inhibitor: a randomized controlled trial
Mayo Clin Proc. 1999 Nov;74(11):1095-105Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
1003 patients with symptomatic knee osteoarthritis were randomized to be administered either celecoxib 50mg twice daily (b.i.d.), celecoxib 100mg b.i.d., celecoxib 200mg b.i.d., naproxen b.i.d., or placebo. Patients were assessed for efficacy and safety measures over 12 weeks of treatment. Reduction in Western Ontario and McMaster Universities Osteoarthritis Index total scores and OA Severity Inde...
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