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ISAKOS2017: Comparison of safety and efficacy between topical and IV tranexamic acid in TKA

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Ace Report Cover
July 2017

ISAKOS2017: Comparison of safety and efficacy between topical and IV tranexamic acid in TKA

Vol: 6| Issue: 7| Number:43| ISSN#: 2564-2537
Study Type:Meta analysis
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Comparison of topical and intravenous tranexamic acid on efficacy and safety in primary total knee arthroplasty, a meta-analysis

Contributing Authors:
J Dong B Chen HT Xu

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CONFERENCE ACE REPORTS

This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.

Synopsis

Eight randomized controlled trials were included in this meta-analysis comparing the efficacy and safety of topical and intravenous tranexamic acid for use in total knee arthroplasty. Total blood loss, postoperative blood loss, hemoglobin (Hb) drop, transfusion rate, and the incidence of complications were pooled. No significant differences between groups were noted, with the exception of Hb drop ...

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