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ISAKOS2017: Comparison of safety and efficacy between topical and IV tranexamic acid in TKA
July 2017
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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.
Synopsis
Eight randomized controlled trials were included in this meta-analysis comparing the efficacy and safety of topical and intravenous tranexamic acid for use in total knee arthroplasty. Total blood loss, postoperative blood loss, hemoglobin (Hb) drop, transfusion rate, and the incidence of complications were pooled. No significant differences between groups were noted, with the exception of Hb drop ...
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