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Volume:5 Issue:6 Number:23 ISSN#:2563-5476
ACE Report #9709
Ace Report Cover Arthroplasty

COA2017: IA TXA reduces blood loss, not transfusion rate, in THA and TKA

Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Low dose intra-articular tranexamic acid reduces hemoglobin drop and D-dimer formation after total hip and knee replacements: doubled-blinded RCT

Contributing Authors: D Hedden E Bohm T Turgeon S Aragola CD Burnell

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


127 patients scheduled for either total hip arthroplasty or total knee arthroplasty were randomized to be administered either 0.5g intraarticular tranexamic acid or saline at the end of the procedure. Patients were assessed for haemoglobin drop, calculated total blood loss, transfusion rate, troponin levels, and d-dimer levels postoperatively. While Hb drop did not significantly differ between gro...

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