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Leukocyte-poor platelet-rich plasma vs hyaluronic acid in treatment of symptomatic knee OA
October 2017
Leukocyte-poor platelet-rich plasma vs hyaluronic acid in treatment of symptomatic knee OA
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Hyaluronic Acid Versus Platelet-Rich Plasma: A Prospective, Double-Blind Randomized Controlled Trial Comparing Clinical Outcomes and Effects on Intra-articular Biology for the Treatment of Knee Osteoarthritis
Am J Sports Med. 2017 Feb;45(2):339-346Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
111 patients with Kellgren-Lawrence grade I-IV symptomatic knee osteoarthritis were randomized to three weekly intraarticular injections of either leukocyte-poor platelet-rich plasma (LP-PRP) or hyaluronic acid. Patients were assessed for pain and function over a 52-week follow-up. The primary outcome measure, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain score, d...
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