ACE Report #9602
Ace Report Cover Arthroplasty

AAOS2017: Narcotic-sparing effect noted with gabapentin use in total knee arthroplasty

Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Does Gabapentin Affect Pain Control and Functional Outcome in Total Knee Arthroplasty? A Randomized Controlled Trial

Contributing Authors: CA Winkler AN Wooldridge GW Brindley MD Jenkins CT Caroom CR Beicker E Larumbe-Zabala

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


50 patients scheduled for total knee arthroplasty were randomized to either perioperative gabapentin or placebo administration. Patients were assessed on postoperative days 0, 1, and 2 for pain scores on a visual analog scale, narcotic consumption, and knee range of motion. Results demonstrated no significant difference in VAS pain scores between groups on POD0-2, or in narcotic consumption on POD...

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