Optimizing TXA administration in bilateral TKA

Study Type:Therapy

OE Level Evidence:2

Journal Level of Evidence:N/A

Optimizing effectivity of tranexamic acid in bilateral knee arthroplasty - A prospective randomized controlled study

Knee. 2017 Jan;24(1):100-106

Contributing Authors: J Singh RN Maniar T Singhi A Patil G Kumar P Maniar

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OE EXCLUSIVE

Synopsis

83 patients undergoing bilateral simultaneous total knee arthroplasty were included in this randomized trial to evaluate the comparative efficacy of three different methods of tranexamic acid (TXA) administration. Patients were randomized to receive one pre-operative and two intra-operative intravenous dosages, two intra-operative intravenous dosages, or two intraoperative local applications of TX...