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Efficacy of fibrin sealant in total hip and total knee arthroplasty

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Ace Report Cover
August 2017

Efficacy of fibrin sealant in total hip and total knee arthroplasty

Vol: 6| Issue: 8| Number:6| ISSN#: 2564-2537
Study Type:Meta-analysis/Systematic Review
OE Level Evidence:2
Journal Level of Evidence:N/A

Topical use of topical fibrin sealant can reduce the need for transfusion, total blood loss and the volume of drainage in total knee and hip arthroplasty: A systematic review and meta-analysis of 1489 patients

Int J Surg. 2016 Dec;36(Pt A):127-137

Contributing Authors:
J Li HB Li XC Zhai Qin-Lei XQ Jiang ZH Zhang

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Synopsis

18 randomized controlled trials were included in this meta-analysis investigating the efficacy and safety of fibrin sealant on reducing blood loss in total knee arthroplasty and total hip arthroplasty. Control groups consisted of either no fibrin sealant administration or placebo administration. Analyses demonstrated significantly lower incidence of transfusion and significantly lower total blood ...

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