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RCT
ACE Report #9423
Ace Report Cover Arthroplasty

Intracapsular and intravenous administration for TXA similar in efficacy and safety in TKA


Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

The Assessment of Blood Loss During Total Knee Arthroplasty When Comparing Intravenous vs Intracapsular Administration of Tranexamic Acid

J Arthroplasty. 2016 Nov;31(11):2452-2457

Contributing Authors: JH May GR Rieser RJ Markert RD Bauman CG Williams MW Lawless

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Synopsis

131 patients scheduled for total knee arthroplasty were randomized to tranexamic acid administration via intracapsular injection at the end of the procedure or intravenous injections before and after the procedure. The purpose of this study was to compare blood loss, hemoglobin levels, transfusion rate, and thromboembolic complication rate between groups over the first 3 days postoperatively. Resu...

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