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Tranexamic acid efficacious in reducing blood loss and transfusion in bilateral TKA

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Ace Report Cover
May 2017

Tranexamic acid efficacious in reducing blood loss and transfusion in bilateral TKA

Vol: 6| Issue: 5| Number:3| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Effectiveness and Safety of Fixed-Dose Tranexamic Acid in Simultaneous Bilateral Total Knee Arthroplasty: A Randomized Double-Blind Controlled Trial

J Arthroplasty. 2016 Nov;31(11):2471-2475

Contributing Authors:
X Cao X Chen C Yang J Zhu K Guo Q Zhu

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Synopsis

120 patients scheduled for simultaneous bilateral total knee arthroplasty were randomized to a single, fixed dose of intravenous tranexamic acid or saline. The purpose of this study was to compare blood loss, transfusion rate, and complications between groups. Results demonstrated significantly lower calculated total blood loss and transfusion rate in the TXA group compared to the control group. N...

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