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Author Verified
Meta-analysis
ACE Report #9324
Ace Report Cover Arthroplasty

IV tranexamic acid reduces blood loss and transfusion rate in primary THA


Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A

Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty

Orthopedics. 2016 Sep 1;39(5):e883-92

Contributing Authors: JT Moskal SG Capps

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Synopsis

Sixteen randomized controlled trials (RCTs) were included in this meta-analysis evaluating the efficacy and safety of intravenous tranexamic acid in total hip arthroplasty. All included trials were placebo controlled. Results demonstrated significantly lower blood loss - including intraoperative blood loss, postoperative blood loss, and total blood loss - and transfusion rate with IV TXA versus pl...

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