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Meta-analysis
ACE Report #9240
Ace Report Cover Arthroplasty

Analgesic efficacy of pregabalin and gabapentin following total knee arthroplasty


Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A

A Meta-Analysis on the Use of Gabapentinoids for the Treatment of Acute Postoperative Pain Following Total Knee Arthroplasty

J Bone Joint Surg Am. 2016 Aug 17;98(16):1340-50

Contributing Authors: TW Hamilton LH Strickland HG Pandit

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Synopsis

Eleven randomized controlled trials were included in this meta-analysis analyzing the efficacy of gabapentin and pregabalin for postoperative analgesia following total knee arthroplasty. The control groups used for comparison in the included studies received either placebo or no additional intervention. The results of this meta-analysis demonstrated a statistically significant analgesic and opioid...

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