Topical TXA reduces blood loss compared to IV TXA in bilateral total knee arthroplasty
Topical TXA reduces blood loss compared to IV TXA in bilateral total knee arthroplasty
Topical vs Intravenous Tranexamic Acid in Reducing Blood Loss After Bilateral Total Knee Arthroplasty: A Prospective Study
J Arthroplasty. 2016 Jul;31(7):1442-8Synopsis
70 patients scheduled for simultaneous bilateral total knee arthroplasty were randomized to administration of intravenous or topical tranexamic acid. The purpose of this study was to compare, primarily, haemostatic efficacy and safety between the two groups, perioperatively, as well as clinical outcomes at follow-up. The results of this trial demonstrated that the estimated total blood loss, posto...
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