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Vitamin D supplementation for bone mineral density increase in osteogenesis imperfecta
September 2016
Vitamin D supplementation for bone mineral density increase in osteogenesis imperfecta
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A
Effect of high-dose vitamin D supplementation on bone density in youth with osteogenesis imperfecta: A randomized controlled trial
Bone. 2016 May;86:36-42Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
60 youth and adolescent patients with osteogenesis imperfecta (OI) were randomized to either high-dose vitamin D supplementation (2000IU daily) or low-dose vitamin D supplementation (400IU daily). The purpose of this study was to evaluate if high-dose supplementation led to a significant increase in areal bone mineral density (aBMD) z-score of the lumbar spine compared to low-dose supplementation ...
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