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Comparison of topical and intravenous tranexamic acid in total hip arthroplasty
August 2016
Comparison of topical and intravenous tranexamic acid in total hip arthroplasty
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Topical vs Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty: A Double-Blind, Randomized Controlled Trial
J Arthroplasty. 2016 May;31(5):1022-6Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
139 patients scheduled for primary unilateral total hip arthroplasty were randomized to administration of either topical tranexamic acid (TXA) or intravenous tranexamic acid. Groups were compared regarding total calculated blood loss, hemoglobin drop, incidence of transfusion, and development of thromboembolic complications. Despite significantly greater blood loss and hemoglobin drop in the topic...
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