WCO-IOF 2016: Alfacalcidol (Vit D analogue) vs. cholecalciferol (Vit D) for osteoporosis

Study Type:Randomized Trial

OE Level Evidence:N/A

Journal Level of Evidence:N/A

The effect of alfacalcidol and plain vitamin D on osteoporosis: a randomized controlled trial

Contributing Authors: BP Shrestha J Kathabania

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Synopsis

80 patients with osteoporosis were randomized to receive either alfacalcidol, a vitamin D analogue, or plain vitamin D (cholecalciferol). Both treatment groups also received calcium supplementation and alendronate. The purpose of this study was to compare the effects on bone mineral density and T-score between alfacalcidol and cholecalciferol. Results demonstrated no significant differences betwee...