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WCO-IOF 2016: Denosumab versus zoledronic acid following oral bisphosphonate therapy
May 2016
WCO-IOF 2016: Denosumab versus zoledronic acid following oral bisphosphonate therapy
Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A
A randomized double-blind study of denosumab (DMAB) compared with zoledronic acid (ZOL) in postmenopausal women with osteoporosis previously treated with oral bisphosphonates
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CONFERENCE ACE REPORTS
This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.
Synopsis
643 postmenopausal women with osteoporosis who had been administered oral bisphosphonates for 2 or more years prior to enrollment were randomized to be administered either denosumab or zoledronic acid. The purpose of this study was to compare the change in bone mineral density (BMD) and bone turnover markers after 1 year. Results demonstrated a significantly greater percent increase in BMD - inclu...
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