WCO-IOF 2016: Greater BMD increase after 1 year of romosozumab vesus teripratide

How to Cite

OrthoEvidence. WCO-IOF 2016: Greater BMD increase after 1 year of romosozumab vesus teripratide. ACE Report. 2016;5(5):15. Available from: https://myorthoevidence.com/AceReport/Report/8930

Study Type:Randomized Trial

OE Level Evidence:N/A

Journal Level of Evidence:N/A

Superior gains in bone mineral density and estimated strength at the hip for romosozumab compared with teriparatide in women with postmenopausal osteoporosis transitioning from bisphosphonate therapy

Contributing Authors: J Malouf B Langdahl C Libanati DB Crittenden K Engelke JS Finkelstein HK Genant S Goemaere L Hyldstrup E Jodar-Gimeno TM Keaveny D Kendler P Lakatos J Maddox FE Massari JF Molina MR Ulla A Grauer

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Synopsis

436 postmenopausal women with osteoporosis who had been administered oral bisphosphonate therapy for 3 years prior were randomized in a phase 3 clinical trial to subcutaneous romosozumab or subcutaneous teriparatide. The purpose of this study was to compare the change in bone mineral density after 1 year of treatment between the two groups. Reported results demonstrated a significantly greater inc...