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Volume:5 Issue:4 Number:46 ISSN#:2563-5476
ACE Report #8849
Ace Report Cover Osteoarthritis

OARSI 2016: Invossa (TissueGene-C) gene therapy beneficial in knee OA vs. placebo

How to Cite

OrthoEvidence. OARSI 2016: Invossa (TissueGene-C) gene therapy beneficial in knee OA vs. placebo . ACE Report. 2016;5(4):46. Available from: https://myorthoevidene.com/AceReport/Report/8849

Study Type:Therapy
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Invossatm(tissuegene-c) in patients with osteoarthritis: a phase III trial

Contributing Authors: J Cho T Kim Y Park J Shin S Kang

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


156 patients with knee osteoarthritis were included in this study and randomized to receive a single injection of either Invossa (TissueGene-C) gene therapy, containing non-transformed and transduced chondrocytes, or saline. The study was conducted in order to determine if the gene therapy was effective in improving cartilage integrity via assessing clinical outcomes at 1 year. The findings of thi...

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