Recombinant human bone morphogenetic protein-7 ineffective in spinal fusion vs. control
Union Rate and Complications in Spine Fusion with Recombinant Human Bone Morphogenetic Protein-7: Systematic Review and Meta-AnalysisGlobal Spine J. 2016 Mar;6(2):124-32
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6 studies with 442 patients were included in this analysis which was conducted in order to determine if recombinant human bone morphogenetic protein-7 (rhBMP-7) was safe and effective in promoting bone formation in spinal fusion. The findings of this study question the clinical relevance of this treatment as comparable rates of union, complications, postoperative back and leg pain, and revision we...
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