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Recombinant human bone morphogenetic protein-7 ineffective in spinal fusion vs. control
August 2016
Recombinant human bone morphogenetic protein-7 ineffective in spinal fusion vs. control
Study Type:Meta-analysis/Systematic Review
OE Level Evidence:2
Journal Level of Evidence:N/A
Union Rate and Complications in Spine Fusion with Recombinant Human Bone Morphogenetic Protein-7: Systematic Review and Meta-Analysis
Global Spine J. 2016 Mar;6(2):124-32Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
6 studies with 442 patients were included in this analysis which was conducted in order to determine if recombinant human bone morphogenetic protein-7 (rhBMP-7) was safe and effective in promoting bone formation in spinal fusion. The findings of this study question the clinical relevance of this treatment as comparable rates of union, complications, postoperative back and leg pain, and revision we...
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